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The development of a new test (prePGTSeq-M) generally requires a maximum of 40 working days from the date Juno receives all the DNA samples and the associated documentation. Once Juno has confirmed that the test is ready, the IVF cycle can be started. The embryos obtained can be biopsied and the samples sent to Juno. PGTseq-M results are generally available within 10 working days after Juno receives the embryo biopsy samples.

Our goal is to make working with Juno Genetics as easy as possible. Juno is committed to support the clinics we work with by providing guidance at all stages of the PGT process. We are available to help with queries and provide advice. At Juno we understand different clinics may have unique needs and our policy is based on flexibility, where we adapt to the specific requirements of each clinic. If your clinic already offers PGT in collaboration with another genetic laboratory, then it is likely that very few, if any, significant changes will be necessary. Please contact Juno Genetics and we will be happy to guide you through the registration procedure, providing you with all the necessary documentation and solving any questions you may have. If your clinic is new to PGT, Juno can assist by providing information and documentation to help you get started. Juno can also assist with training and evaluation of procedures, ensuring that all elements of the PGT procedure are optimized and functioning properly, prior to launch a clinical service. Please contact supportspain@junogenetics.com to get started with Juno.

A detailed explanation of the PGTseq-M method and its requirements is included in the Juno Genetics Instruction Manual. In summary, Juno will start working on a new PGTseq-M test (prePGT-M) once the following is received: 1) genetic reports describing the mutation(s) responsible for the disorder(s) for which PGTseq-M is requested; 2) blood samples from the couple requesting PGTseq-M (both male and female, even if only one of them is carrier of the mutation); 3) whenever possible, a blood, DNA or saliva sample from a child or the patient’s mother/father tested for the mutation; 4) a completed test request form for PGTseq-M which includes relevant patient information, including genetic information. A prePGT-M test requires several weeks to be developed in each case. Although in most cases, the prePGT-M will have a successful outcome, in rare cases it will be technically not feasible. For these reasons, patients should not start an IVF cycle until Juno has confirmed that the prePGT-M test has been successfully developed.

The time required for the shipment of the samples, and for the complex laboratory procedures, means that the embryos must be cryopreserved (vitrified) while the test is being performed. The embryos can usually be thawed and transferred during the next cycle.

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